The #1 Wiki source of information for The Binding of Isaac: Rebirth, the randomly generated action RPG shooter with heavy Rogue-like elements. Check out the guides, characters, summaries and more!
Usable items are items that the player can hold, only one at a time, that recharge as you complete rooms. Each item has their own charge amount, depending on how powerful the effects are.
Anarchist Cookbook | Anarchist cookbook.png | Spawns 6 troll bombs in random locations in the room. |
Bean, The | Bean.png | Causes the player to fart, poisoning any nearby enemy. |
Best Friend | Best_friend.png | Puts down a doll that attracts enemies and eventually explodes. |
Bible, The | Bible.png | The player gains flight. Instantly kills Mom, Mom's Heart, or It Lives! when activated. Will kill the player if used against Satan, Isaac, ???, or Mega Satan, unless they have the Wafer permanent item. |
Blank Card | Blank_card.png | Same effect of any card/rune the player is carrying. Unlocked by beating Isaac with Eden. |
Blood Rights | Blood_rights.png | Takes away a half-heart from the player, damaging all enemies in the room. Unlocked by beating Satan with Samson. |
Bob's Rotten Head | Bob's_head.png | Throws a bombs in the direction the player chooses and explodes on contact, poisoning and damaging all enemies hit. |
Book Of Belial, The | Book_o_belial.png | Damage Up for the current room. |
Book Of Revelations | Book_of_rev.png | Adds 1 soul heart and increases the chances for the boss to be a horseman. Unlocked by beating a horseman for the first time. |
Book Of Secrets | Book_of_secrets.png | Chance to get one of the following effects: Treasure Map (floor layout), Compass (map icons), or Blue Map (secret room locations). Unlocked by beating Satan with Eden. |
Book Of Shadows | Book_of_shadows.png | Grants invulnerability for 10 seconds. |
Book Of Sin, The | Book_of_sin.png | Spawns a random pick-up. Unlocked by beating each of the Seven Sin mini-bosses once. |
Boomerang, The | Boomerang.png | Throws a boomerang in the direction the player chooses, stunning enemies and dealing a small amount of damage. Will move pick-ups. |
Box Of Spiders | 20141111142501!Box Of Spiders Icon.png | Spawns 2-4 friendly spiders. |
Breath Of Life | 20141111142540!Breath Of Life Icon.png | No damage from tears as long as you hold it down. Holding it down too long will cause you to take damage. |
Butter Bean | 20141111142603!Butter Bean Icon.png | Farts on nearby enemies and knocks them away from the player. Unlocked by destroying 100 poops. |
Candle, The | 20141111142726!The Candle Icon.png | Fires a blue flame that damages anything in it's path. Unlocked by donating 900 coins. |
Converter | Converter.png | Converts 2 soul/black hearts into 1 red heart container. |
Crack The Sky | On crack.png | Beams of light come down at random locations in the room, dealing damage to enemies. |
Crystal Ball | Crystal ball.png | Reveals the entire map and gives the player a random tarot card or soul heart. |
D4 | 20141111143343!D4 Icon.png | Rerolls all items you currently have. Unlocked by blowing up 30 Slot Machines. |
D6, The | 20141111143315!The D6 Icon.png | Rerolls any items into another item. Unlocked by beating Isaac with Blue Baby. |
D10 | 20141104234040!D10 Icon.png | Rerolls all enemies in the room. Cannot reroll mini-bosses or bosses. |
D20 | 20141111143421!D20 Icon.png | Rerolls all pick-ups in the room with another random pick-up. Unlocked by beating The Chest with Isaac. |
D100 | D100.png | Rerolls all items you currently own and any items/pick-ups in the room. Unlocked by beating the Boss Rush Room with The Lost. |
Dad's Key | 20141111143711!Dad's Key Icon.png | Opens all closed doors in the current room, except locked rooms and Secret Rooms. Can also be used to open the Golden Door that appears in the Dark Room or The Chest. Unlocked by collecting both Key Pieces from the Angel mini-bosses. |
Dead Sea Scrolls | Dead.png | Random usable item effect. |
Deck Of Cards | Deck.png | Gives a random tarot card. |
Doctor's Remote | Remote.png | Spawns a target on the floor near the player, which can be controlled. After a few seconds, a huge missile hits the target, exploding and dealing damage to anything nearby. Essentially a one time use of the Epic Fetus permanent item. |
Flush! | Woosh.png | Turns every normal enemy in the room into poop. Does not work on mini-bosses or bosses. |
Forget Me Now | Forget me now.png | Refreshes the current floor entirely with new rooms, monsters, and items. Does not revet the player back to the state they were in when they had gotten the item, only the floor they were on. Unlocked by beating Satan with Blue Baby. |
Gamekid, The | Gamekid.png | Turns the player into pacman, making him invincible and grants contact damage. If you kill an enemy in this state, you regain health. Unlocked by visiting 10 arcades. |
Guppy's Head | 20141111144902!Guppy's Head Icon.png | Spawns several friendly flies. |
Guppy's Paw | Paw.png | Replaces 1 red heart container with 3 soul hearts. |
Head Of Krampus | Head.png | Shoots Brimstone in all horizontal and vertical directions, dealing damage to any enemies. Unlocked by beating Krampus. |
Hourglass, The | Hour.png | Slows down all enemies in the current room, including their projectiles. |
How To Jump | How to jump.png | Causes the player to leap into the air in the direction they choose. Becomes a dash effect instead if you have flight. |
Isaac's Tears | Isaac's tears.png | Fires 8 tears in a circle around him. Unlocked by beating Isaac with Isaac. |
IV Bag | 20141111145147!IV Bag Icon.png | Takes a red half-heart and spawns some coins. Same effect as the Blood Donation machine. |
Jar, The | 20141111145231!The Jar Icon.png | Picks up hearts while at full health, which can be spawned by using the item. |
Kamikaze! | 20141111145610!Kamikaze! Icon.png | Explodes the player, causing you to lose 1 heart and damaging any nearby enemies. |
Lemon Mishap | 20141111145622!Lemon Mishap Icon.png | Drops a pool of 'lemonade' onto the floor, damaging any enemies who come in contact with it. |
Magic Fingers | 20141111145650!Magic Fingers Icon.png | Damages all enemies in the room for a price of 1 coin. |
Mom's Bottle Of Pills | 20141111145712!Mom's Bottle Of Pills Icon.png | Gives a random pill. |
Mom's Bra | 20141111145736!Mom's Bra Icon.png | Freezes all enemies in the room. |
Mom's Pad | 20141111145751!Mom's Pad Icon.png | Causes all enemies to run away from the player for several seconds. |
Monster Manual | 20141111145803!Monster Manual Icon.png | Spawns a random familiar for the duration of the room. |
Monstro's Tooth | 20141111150227!Monstro's Tooth Icon.png | Monstro jumps onto a random enemy in the room, dealing massive damage. Unlocked by beating Basement II for the first time. |
Mr. Boom | 20141111150243!Mr. Boom Icon.png | Drops a large bomb which explodes after several seconds. |
My Little Unicorn | 20141111150257!My Little Unicorn Icon.png | Grants the player invulnerability, damaging any enemies they come in contact with. Speed Up while the effect is resolving. |
Nail, The | 20141111150312!The Nail Icon.png | Adds 1 soul heart. Damage Up, Speed Down, and the player can destroy any breakable objects for the duration of the room. Unlocked by beating the Boss Rush Room with Azazel. |
Necronomicon, The | 20141111150333!The Necronomicon Icon.png | Damages everything in the room. Unlocked by using 4 Death Cards. |
Notched Axe | 20141111150658!Notched Axe Icon.png | Destroys all breakable items and reveals any Secret Room doors in the current room. |
Pandora's Box | 20141111150722!Pandora's Box Icon.png | Spawns a random item and 2 soul hearts. Can only be used once. Unlocked by beating The Dark Room with Lazarus. |
Pinking Shears, The | 20141111150821!The Pinking Shears Icon.png | Grants flight and a small familiar of the player's body that tries to attack enemies if they get close enough. |
Pony, The | 20141111150839!The Pony Icon.png | Grants flight while being held. Speed is increased by 3 while being held, and further Speed Ups do not affect the player until you stop using the item. The active effect causes the player to dash in the current direction and deals contact damage. |
Poop, The | 20141111150857!The Poop Icon.png | Spawns a poop where the player is. |
Portable Slot | 20141111151026!Portable Slot Icon.png | Acts like a Slot Machine. |
Prayer Card | 20141111151103!Prayer Card Icon.png | Gives the player an eternal heart. |
Razor Blade | Razor.png | Deals damage to the player for a Damage Up in the current room. Unlocked by beating Satan with Eve. |
Red Candle | Red candle.png | Similar to the Candle usable item, however, the flame stays for the duration of the room if it doesn't touch anything. As it deals damage, it will eventually shrink and dissapear. Unlocked by donating 400 coins to the Shop. |
Satanic Bible | 20141111151257!Satanic Bible Icon.png | Gives the player 5 bombs, and all bombs only explode when you use the item. |
Remote Detonator | 20141111151240!Remote Detonator Icon.png | Gives the player a black heart. Unlocked by beating Isaac with Azazel. |
Scissors | Scissors.png | Similar to Pinking Shears, however you can control the body. The head will remain stationary and shoot tears in the direction you are firing. Unlocked by dying 100 times. |
Shoop Da Whoop! | 20141111151818!Shoop Da Whoop! Icon.png | Fires a brimstone-like shoot in the direction you are facing. |
Spider Butt | 20141109225619!Spider Butt Icon.png | Damages all enemies in the room and slows them, along with their projectiles. |
Tammy's Head | 20141111151855!Tammy's Head Icon.png | Shoots 10 tears in a circle around the player. |
Telepathy For Dummies | 20141111151912!Telepathy For Dummies Icon.png | The player gains homing shots for the current room. |
Teleport | 20141111151923!Teleport Icon.png | Teleports the player to a random location. |
Undefined | 20141111151939!Undefined Icon.png | Teleports you to one of the following rooms: Item Room, Secret Room, Super Secret Room, Curse Room, I AM ERROR Room, or a Black Market Room. UNlocked by beating the Boss Rush Room with Eden. |
Unicorn Stump | 20141111152015!Unicorn Stump Icon.png | Similar to the My Little Unicorn usable item, however, will not deal contact damage. |
We Need To Go Deeper! | Shovel.png | Spawns a trapdoor which allows the player to either travel to the next floor or go to a Retro Treasure Room. |
White Pony | 20141111152138!White Pony Icon.png | Similar to the Pony usable item, however, the active effect also has the effect of the Crack The Sky usable item. |
Yum Heart | 20141111152150!Yum Heart Icon.png | Heals the player for 1 red heart. |
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